Human genome sequencing
- Sadia Afsari
- May 6, 2023
- 2 min read

The human genome is the whole set of
genetic statistics contained within the DNA
of a individual. The sequencing of the
human genome turned into a enormous
medical fulfillment that has transformed
our understanding of human biology and
sickness.
The process of sequencing the human
genome commenced inside the early
Nineteen Nineties and took greater than a
decade to complete. The initial stage
concerned the improvement of technology
for speedy DNA sequencing. This
generation, called shotgun sequencing,
includes breaking up the genome into small
fragments, sequencing each fragment, and
then piecing the fragments again together
like a jigsaw puzzle.
As soon as the technology become in
vicinity, the actual sequencing manner
started. The primary genome to be
sequenced changed into that of Craig
Venter, a private researcher who used a
new technique referred to as
complete-genome shotgun sequencing.
This method involves randomly breaking
the DNA into small fragments after which
using computers to collect them in the
perfect order.
The general public assignment to collection
the human genome, the Human Genome
challenge, commenced in 1990. It was an
international collaboration involving
scientists from round the sector, with the
goal of sequencing the whole human
genome and making the records freely to
be had to the general public.
The sequencing technique involved the
collection of DNA samples from volunteers,
the extraction of the DNA from the cells,
and the fragmentation of the DNA into
smaller portions. The DNA fragments had
been then sequenced the use of automatic
machines that read the series of
nucleotides in every fragment.
The sequencing manner generated a
widespread amount of facts that needed to
be analyzed and assembled. This required
the development of state-of-the-art
computer algorithms that might piece
together the DNA fragments and become
aware of the genes and different purposeful
elements in the genome.
The final touch of the human genome
undertaking in 2003 marked a chief
milestone inside the history of biology. The
challenge provided a blueprint of the
human genome that has revolutionized our
information of human biology and ailment.
It has brought about the identity of many
disease-causing genes and the
development of new treatments for genetic
problems.
In conclusion, the sequencing of the human
genome changed into a complicated and
challenging method that required the
improvement of latest technologies and
computational techniques. The crowning
glory of the project has converted our
expertise of human biology and unfolded
new avenues for the improvement of
treatments for genetic illnesses.
Author-
Name: Sabeda khatun Ontora
Institute: Feni Govt college
E-mail: ashrafulislamnadim@gmail.com
Коментарі