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Human genome sequencing

  • Sadia Afsari
  • May 6, 2023
  • 2 min read

The human genome is the whole set of

genetic statistics contained within the DNA

of a individual. The sequencing of the

human genome turned into a enormous

medical fulfillment that has transformed

our understanding of human biology and

sickness.


The process of sequencing the human

genome commenced inside the early

Nineteen Nineties and took greater than a

decade to complete. The initial stage

concerned the improvement of technology

for speedy DNA sequencing. This

generation, called shotgun sequencing,

includes breaking up the genome into small

fragments, sequencing each fragment, and

then piecing the fragments again together

like a jigsaw puzzle.


As soon as the technology become in

vicinity, the actual sequencing manner

started. The primary genome to be

sequenced changed into that of Craig


Venter, a private researcher who used a

new technique referred to as

complete-genome shotgun sequencing.

This method involves randomly breaking

the DNA into small fragments after which

using computers to collect them in the

perfect order.


The general public assignment to collection

the human genome, the Human Genome

challenge, commenced in 1990. It was an

international collaboration involving

scientists from round the sector, with the

goal of sequencing the whole human

genome and making the records freely to

be had to the general public.


The sequencing technique involved the

collection of DNA samples from volunteers,

the extraction of the DNA from the cells,

and the fragmentation of the DNA into

smaller portions. The DNA fragments had

been then sequenced the use of automatic

machines that read the series of

nucleotides in every fragment.


The sequencing manner generated a

widespread amount of facts that needed to

be analyzed and assembled. This required

the development of state-of-the-art

computer algorithms that might piece

together the DNA fragments and become

aware of the genes and different purposeful

elements in the genome.


The final touch of the human genome

undertaking in 2003 marked a chief

milestone inside the history of biology. The

challenge provided a blueprint of the

human genome that has revolutionized our

information of human biology and ailment.

It has brought about the identity of many

disease-causing genes and the

development of new treatments for genetic

problems.


In conclusion, the sequencing of the human

genome changed into a complicated and

challenging method that required the

improvement of latest technologies and

computational techniques. The crowning


glory of the project has converted our

expertise of human biology and unfolded

new avenues for the improvement of

treatments for genetic illnesses.


Author-

Name: Sabeda khatun Ontora

Institute: Feni Govt college

E-mail: ashrafulislamnadim@gmail.com

 
 
 

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